Matthew Gideon (Gary Cole): Captain of the Excalibur. He was rescued by Galen ten years before when his ship was blown up
Elizabeth Lochley (Tracy Scoggins): Captain and commander of Babylon 5. She and Gideon develop a grudging relationship.
John Matheson (Daniel Dae Kim): He is Gideon's trusted first officer. He is the highest profile telepath who has joined the military sunder the new rules following the Telepath War.
Max Eilerson (David Allen Brooks): He is an archaeologist who works for IPX.
Galen (Peter Woodward): He is a technomage, who comes and goes as he pleases and harbors many secrets.
Dr. Sarah Chambers (Marjean Holden): She is the ship's doctor, who as such is on the frontline for finding a cure for the plague.
Dureena Nafeel (Carrie Dobro): She is a member of the Thieves' Guild and is the last member of her race, which was wiped out by the Shadows.
Trace Miller (Alex Mendoza): He is a skilled shuttle pilot.
