January 17 - Andrew Pickens commands the militia at the Battle of Cowpens, South Carolina. January - Andrew Pickens is promoted to brigadier general.
- Andrew Pickens' militia is disbanded as they are recalled to defend their homes. April - Andrew Pickens raises a regiment of "state regulars." May 22 - Andrew Pickens is present at the Siege of Augusta, Georgia. June 5 - Colonel Thomas Brown surrenders Augusta, Georgia. June - Andrew Pickens joins Maj. General Nathanael Greene's siege of Ninety-Six, South Carolina. June 11 - Andrew Pickens is ordered to aid Thomas Sumter in blocking a relief column. June 19 - Maj. General Nathanael Greene abandons his siege of Ninety-Six, South Carolina. September 8 - Andrew Pickens participates in the Battle of Eutaw Springs, South Carolina. November - Andrew Pickens leads a campaign against the Cherokee Indians.
1782 September - Andrew Pickens and Elijah Clarke secure claims for the state of Georgia from the Indians for all lands south of the Savannah River and east of the Chattahoochie River.
- Andrew Pickens is elected to the Jacksonboro Assembly to represent the Ninety-Six District.
- Andrew Pickens is elected to Congress.
1817 August 11 - Andrew Pickens dies.
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