- Isaac Shelby completes his home, Traveller's Rest.
1787
- Isaac Shelby attends a Kentucky statehood convention.
1788
- Isaac Shelby attends a Kentucky statehood convention.
1789
- Isaac Shelby attends a Kentucky statehood convention.
1791 Janaury - Isaac Shelby is selected as a member of Board of War of the District of Kentucky.
1792 April - Isaac Shelby helps frame Kentucky's first constitution. May - Isaac Shelby is elected the first Governor of Kentucky. June 4 - Isaac Shelby takes office.
1796
- Isaac Shelby ends his term as Governor of Kentucky.
1797
- Isaac Shelby serves as a presidential elector.
1801
- Isaac Shelby serves as a presidential elector.
1805
- Isaac Shelby serves as a presidential elector.
1812
- Isaac Shelby is again elected Governor of Kentucky.
1813 October 5 - Isaac Shelby is present at the Battle of the Thames, Canada.
1819
- Isaac Shelby becomes the chairman of the first board of trustees of Centre College.
1826 July 18 - Isaac Shelby dies at Traveller's Rest, Lincoln County, Kentucky.
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